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Researchers observed that BPC-157 is associated with upregulation of growth factor receptor expression, including VEGFR2 and FGFR, which may contribute to its studied effects on angiogenesis

Y.WuM.ZhaoD.EdwardsD.McVicarA.LuoY.et al (2021)

This oxidative stress not only exacerbates the inflammatory response within follicular sebaceous gland units but also promotes apoptosis and the release of MMPs, further compromising skin barrier integrity (Xu et al., 2019